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In vitro colonic fermentation of dietary fibers: fermentation rate, short-chain fatty acid production and changes in microbiota

This is based on the role of SAM as both an allosteric activator of cystathionine -synthase and an allosteric inhibitor of MTHFR, the enzyme that produces 5-methyltetrahydrofolate (Figure 2)

B.SilvestriC.et al

6g) reveals that the backbone atoms of GSH_c experience some deviation at around 50 ns and 180 ns, stabilizing after 200 ns and maintaining this stability until 500 ns