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A 2015 meta-analysis found that NAC reduced chronic bronchitis or COPD exacerbations, though later research has been mixed, including a 2024 trial in mild-to-moderate COPD that did not find a significant reduction in overall exacerbation rates with high-dose NAC.1 22 Fertility Oxidative stress can damage sperm, eggs, and the reproductive environment, which is one reason antioxidants are often studied in fertility research

One analysis of the U.S

10.1007/s12094-012-0785-3 13 ChengJ.HaM.WangY.SunJ.ChenJ.WangY.et al

Am J Respir Crit Care Med 195(9):11811188 Baan EJ, de Roos EW, Engelkes M, de Ridder M, Pedersen L, Berencsi K et al (2022) Characterization of asthma by age of onset: A Multi-Database cohort study