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We expect that this pathway will be relevant to the physiology and pathophysiology of liver, muscle, adipose, and other highly metabolically active cell types

[PMC free article] [PubMed] 4.Park E., Park S.Y., Dobkin C., Schuller-Levis G

MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation. 2023

A growing body of evidence has identified disrupted copper homeostasis and subsequent activation of cuproptosis as key upstream drivers of this maladaptive process [98]