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MYC-driven mitochondrial metabolic rewiring increases DLAT expression and cuproptosis sensitivity in group-3 medulloblastomas, whereas DLAT inhibition lowers TCA cycle metabolism and GSH synthesis 175

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[] A recent study reported that in the cardiac tissues of HF patients with diabetes, SIRT6 expression markedly decreased, causing hyperacetylation of PPAR and resulting in cardiac lipid accumulation and diastolic dysfunction

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Andreeff M , Homge-Offenberg M, Goodacre A, Pereira-Leahy M, Tafuri A, Drach J