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japonicum , rSj16, shows protective effects on DSS-induced colitis by inhibiting the peroxisome proliferator-activated receptor (PPAR)-alpha- signaling pathway [166] and reducing apoptosis [167]

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doi: 10.1056/NEJMoa1506197 82 BuqueABloyNPetroniGKroemerGGalluzziL

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Glutathione, particularly reduced glutathione (GSH), represents a principal anitioxidant that could decrease ROS through scavenging them directly or indirectly through ascorbateglutathione cycle or GSH peroxidases