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The emphasis is usually on signaling balance rather than raw cell proliferation

In germ-free mice, colonization with this bacterium could restore the expression of key neurotransmitter-synthesizing enzymes in enteric neurons, including choline acetyltransferase, substance P, and nitric oxide synthase 70 .The gut microbiota maintains enteric nervous system integrity and regulates gastrointestinal function in a sex-independent manner via LPS and SCFAs 71