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Kreis NN, Louwen F, Yuan J

Pain Animal studies have shown beneficial effects of B12 on the regeneration of nerves and the inhibition of pain-signalling pathways, including cyclooxygenase enzymes

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Gpx4 fl/wt LysMCre + mice also displayed SLE-like clinical manifestations, including alopecia, lymphadenopathy, splenomegaly, proteinuria, significant increases in anti-dsDNA antibodies, IFN-, IL-6, and decreased complement C3 levels, indicating a close association between decreased neutrophil GPX4 protein expression and SLE pathogenesis

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