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Reports have demonstrated that abnormal DNA methylation has been involved in multiple types of tumorigenesis ( Reports have uncovered that the tumor microenvironment (TME), which consists of tumor cells and many other cells, plays a crucial role in cancer progression and could significantly influence clinical outcomes ( Additionally, through the enrichment analyses of GPX8-related genes, we recognized the Glutathione Metabolism, Antioxidant Activity and Antioxidant Activity may be the potential mechanism for GPX8 to influence the etiology(ies) and pathogenesis of cancers

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10.1016/j.neuropharm.2019.03.002 246 PalyginO.LaloU.PankratovY