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A plaques result from the abnormal cleavage of amyloid precursor protein (APP) by betasecretase (BACE1) and gammasecretase, leading to the aggregation of A peptides, particularly A42, which is highly toxic to neurons (Hardy and Selkoe 2002)

1 AIM-MASH+ is for research use only

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Alterations in gut microbiota composition have been consistently reported in patients with neurodegenerative disorders, and are characterized by reduced levels of neuroprotective compounds, including neurotransmitters and short-chain fatty acids (SCFAs), alongside elevated levels of pro-inflammatory cytokines and harmful compounds such as lipopolysaccharides (LPS)

Boosted metabolism : NAD+ plays a key role in metabolic processes, which can help with weight management and energy balance

By promoting better glucose uptake and utilization , GDAs can help regulate blood sugar levels, reduce insulin resistance, and support overall metabolic health