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doi: 10.3389/fpsyg.2025.1641693 Received 06 June 2025 Accepted 19 August 2025 Published 09 September 2025 Volume 16 - 2025 Edited by Mark Antoniou, Western Sydney University, Australia Reviewed by Alexandra Wolf, RIKEN Center for Advanced Intelligence Project (AIP), Japan Lifeng Tang, Ningbo Rehabilitation Hospital, China Updates Copyright 2025 Maggio, Maione, Cotelli, Bonasera, Corallo, Pistorino, Luca, Marra, Quartarone, Nicoletti and Calabr

The process of aging has been shown to diminish the efficacy of NRF2 activation, thereby complicating treatment outcomes for elderly patients