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The longer half-life for compound CK1/-specific inhibitor (PF-05236216) was advanced into preclinical efficacy studies since it would allow us to have the temporal resolution to study CK1-dependent TDP-43 phosphorylation in vivo

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Methods: A decision tree model projected costs and outcomes associated with POC_RNA and SOC from the Medicaid perspective given expanded coverage of many PWID

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The quantity was characterized using a UV spectrophotometer (NanoDrop 8000, Thermo Scientific, USA)