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Biological activities and bioavailability of mangosteen xanthones: a critical review of the current evidence

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AM, MZ, and NG searched for literature, wrote the manuscript, reviewed and edited the manuscript

In REDEFINE 1 (NEJM 2025, n=3,417, 68 weeks), cagrilintide monotherapy at 2.4 mg produced 11.8% mean body-weight reduction versus 2.3% with placebo