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Published AOD-9604 trials did not report patterns of fluid retention or edema, suggesting this side effect is not a concern with the peptide fragment

Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ (2020) COVID-19: consider cytokine storm syndromes and immunosuppression

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However, if a specialized laboratory test is used, stable metabolites of the peptide can typically be detected for roughly 24 to 48 hours after administration, with some studies suggesting trace detection up to 4 days later

Lahring J, Leifheit-Nestler M, Ewert A, Herzig N, Koppl C, Pott V, Oh J, Buscher A, Thumfart J, Weber LT, Arbeiter K, Acham-Roschitz B, Tonshoff B, Zivicnjak M, Hohenfellner K, Haffner D (2024) Cystinosis-associated metabolic bone disease across ages and CKD stages 15D/T