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Thymidine was added again (final concentration 2 mM) and incubated for 18 h

Purified mouse GDF15 (patent ID: WO2012138919A2) was injected i.p

Reactome pathway analysis results show that cluster A mainly impacts mitochondrial translation processes, while cluster B is involved in respiratory electron transport, chemiosmotic coupling of ATP synthesis, and uncoupling protein-mediated thermogenesis (Figure 5D

Saxenda works by acting on the brain to regulate appetite and food intake

& Park, T

These changes together can reduce hallmarks of oocyte aging: lower ATP, higher ROS, fragmented mitochondria, and dysregulated mtDNA expression