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Pregnancy and Lactation Available data from cases reported in the published literature and postmarketing surveillance with CYANOKIT use in pregnant women are insufficient to identify a drug-associated risk for major birth defects, miscarriage, or adverse maternal and fetal outcomes

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A small pinch at the IV stick most patients rate it 2/10

However, you can learn to administer the shot yourself so that you do not have to go to the physician each time you need a dose