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Unfortunately, many doctors and practitioners are still uneducated on these new therapeutic approaches and continue to use high-dose corticosteroids as a mask for pain and a shotgun approach for many orthopedic ailments even though these types of corticosteroid medications slow healing and cause degenerative atrophy of tendon, ligament, bone, and cartilage due to downregulation of collagen synthesis, thus causing worsening or recurrence of the problem and degenerative feedback cycles

In neuroprotection studies, DSIP has also shown potential benefits in reducing oxidative stress and improving mitochondrial function

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A score of 0 indicates a non-essential gene, while -1 reflects the median for essential genes

Mihalas BP, De Iuliis GN, Redgrove KA, McLaughlin EA, Nixon B