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It contributes to red blood cell production, nerve cell maintenance, and DNA synthesis

Realtime quantitative PCR Total RNA from liver samples or cultured cells was extracted using mirVana miRNA isolation kit (Ambion) and DNase treated with Turbo DNAfree DNase Treatment kit (Ambion) as per manufacturer's protocol

Animal housing and tissue dissection The guidelines of the Institutional Animal Care Committee of The Hebrew University (Jerusalem, Israel) were followed in this study

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Results: A total of 53 studies were included, with 37 reporting AUCs with 95% CI on validation datasets