Similar content being viewed by others Introduction Acute liver injury is caused by various factors, including drug toxicity, viral infections, environmental toxins, and autoimmune diseases
These technologies provide notable benefits in terms of real-time monitoring, targeted release, and multiplexed sensing capabilities when paired with functionalized nanoparticles, which are able to sense, respond, and deliver payloads at the molecular level [24,25,26]
To view a copy of this licence, visit About this article Cite this article Tong, J., Song, J., Zhang, W
Abbreviations 5-MTHF: 5-Methyltetrahydrofolate A: amyloid-beta ALSFRS-R: Revised Amyotrophic Lateral Sclerosis Functional Rating Scale AD: Alzheimers disease ALDH1L2: 10-formyl-THF dehydrogenase ALS: Amyotrophic lateral sclerosis AMPK: Adenosine monophosphate-activated protein kinase ApoE: Apolipoprotein E ASD: Autism spectrum disorder APP: Amyloid precursor protein ATP: adenosine triphosphate BDNF: Brain-derived neurotrophic factor BH2: Dihydrobiopterin BH4: Tetrahydrobiopterin CBS: Cystathionine beta-synthase COMT: Catechol-O-methyl transferase C9orf72: Chromosome 9 open reading frame 72 CSF: Cerebrospinal fluid DHF: Dihydrofolate DHFR: Dihydrofolate reductase dTMP: Deoxythymidine monophosphate dUMP: Deoxyuridine monophosphate eNOS: Endothelial nitric oxide synthase ERK: Extracellular signal-regulated kinase FR: Folate receptor FR: Folate receptor alpha FOCM: Folate-mediated one-carbon metabolism GTPCH: GTP cyclohydrolase I GPx: Glutathione peroxidase GWAS: Genome-wide association study HHcy: Hyperhomocysteinemia Hcy: Homocysteine HD: Huntingtons disease HTT: Huntingtin IL-6: Interleukin-6 iNOS: Inducible nitric oxide synthase LCMT1: Leucine carboxyl methyltransferase LRKK2: Leucine-rich repeat kinase 2 MAPK: Mitogen-activated protein kinase MAT2A: Methionine adenosyltransferase 2 A MTHFD1: Methylenetetrahydrofolate dehydrogenase 1 MTHFD2: Methylenetetrahydrofolate dehydrogenase 2 MTHFD1L: Methylenetetrahydrofolate dehydrogenase 1-like MTHFR: Methylenetetrahydrofolate reductase MTR: Methionine synthase MS: Multiple sclerosis MTRR: Methionine synthase reductase NAD: Nicotinamide adenine dinucleotide NGF: Nerve growth factor NF-B: Nuclear factor kappa-light-chain-enhancer of activated B cells NMDA: N-methyl-D-aspartate NO: nitric oxide NTD: Neural tube defect OCM: one-carbon metabolism PARP: poly-ADP-ribose polymerase PD: Parkinsons disease PCFT: Proton-coupled folate transporter PINK1: PTEN-induced kinase 1 PRKN: Parkin RBR E3 ubiquitin protein ligase PS1: Presenilin 1 ROS: Reactive oxygen species RFC: Reduced folate carrier SAH: S-adenosylhomocysteine SAM: S-adenosylmethionine SHMT1: Serine hydroxymethyltransferase 1 SHMT2: Serine hydroxymethyltransferase 2 alpha SOD1: Superoxide dismutase TARDBP: TAR DNA-binding protein THF: Tetrahydrofolate TNF-: Tumor necrosis factor alpha TYMS: Thymidylate synthase References Ducker GS, Rabinowitz JD
Supporting Natural Detoxification The liver is your bodys primary filtration system
Nothing ever good has come from a negative thought
