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7.5.5 Outcome measurement and definition heterogeneity Substantial heterogeneity exists in how primary outcomes are defined and measured across studies

Kamenicky, P., Mazziotti, G., Lombes, M., Giustina, A

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The thymus starts to atrophy around age 15 and continues to decline until approximately 80-90% of its activity has decreased by age 35-45, which is when the chronic diseases of aging start becoming prevalent

Thus, ChaC1 is as a key regulator of tumor development, metastasis and responses to chemotherapy, targeted therapy and immunotherapy