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Alternate gamma-glutamyl targets include GT1 substrates, including Glutathione di-sulfide (GSSH), leukotriene C4 (LTC4) 6 and S-nitroso-glutathione 7 and GSH-xenobiotic adducts

5) Gaps in ferroptosis and RCC metastasis: Ferroptosis is proposed to contribute to RCC metastasis (232), but the underlying mechanisms are largely unexplored

To better preserve the three-dimensional architecture of the native extracellular matrix (ECM) and replicate the microenvironment required for cell proliferation and differentiation, scaffold-based technologies have been employed to facilitate the directed differentiation of MenSCs

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10.1186/s13229-016-0099-3 167