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Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter. International Journal of Molecular Sciences, vol

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The impact of a single low dose of kratom tea (2 g) on the pharmacokinetics of the CYP3A probe midazolam (2.5 mg) and CYP2D6 probe dextromethorphan (30 mg) were assessed in 12 healthy adult participants after oral administration

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TMP269, a potent and selective class IIa HDACs inhibitor, significantly improves the pathological changes including renal tubular dilation, cell debris accumulation in the renal tubular lumen, interstitial edema, and inflammatory cell infiltration in FA-/IRI-induced AKI mouse model by reducing the expression of HDAC4 to regulate pathways associated with apoptosis, autophagy, and proliferation

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