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A wealth of experimental evidence shows that glutathione is severely depleted in the brains of MS patients, making repletion with IV glutathione a rational therapeutic approach

Additionally, other ABC transporters like ABCB4, ABCG4, and ABCG6 contribute to this resistance by enhancing drug efflux (Prez-Victoria et al., 2011

The proline substitutions at positions 25, 28, and 29 were specifically engineered to suppress the beta-sheet aggregation pathway that destabilises native human amylin in aqueous solution

For those interested in injury healing through peptides , this dual application of PTD-DBM is particularly noteworthy

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An important feature of chronic OIPN is the coasting, in which approximately 60% of patients report long-lasting neuropathic symptoms that significantly impair their quality of life after completing the last chemotherapy course [11, 19]