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A 6-weeks intervention trial using daily supplement with -3 PUFA and vitamin D in 56 couples undergoing IVF or ICSI showed no difference in the second cell cycle (CC2) but faster fourth cell cycle (CC4) and a significantly shorted third cell cycle (S3) improving embryo quality (133)

In such context, it is referred to vitamin D as a neuro-steroid that plays an important role in several process of brain development [119]

For example, ceruloplasmin is a copper-containing ferroxidase that possesses ferroxidase and antioxidant activity and inhibits iron-and copper-dependent lipid peroxidation and scavenging peroxide and superoxide anions

Depression and synaptic zinc regulation in Alzheimer disease, dementia with lewy bodies, and Parkinson disease dementia

Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension

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