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doi: 10.1038/s42004-023-00956-9 106 CollRCSchroderKPelegrnP

such recombinant human antibodies can be subjected to in vitro mutagenesis and thus the amino acid sequences of the V H and V L regions of the recombinant antibodies are sequences that, while derived from and related to human germline V- and V L sequences, may not naturally exist within the human antibody germline repertoire in vivo

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XL, XY, QS, SC, and KD participated in some of the experiments

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