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The control worms displayed a relatively constant ratio of ~18:1, while in AF-treated worms a gradual oxidation of glutathione was detected as early as 1 h of AF treatment

Acknowledgements The authors received no funding for the publication of this work

PubMed Ho, E.N., Kwok, W.H., Lau, M.Y., Wong, A.S., Wan, T.S., Lam, K.K., Schiff, P.J., Stewart, B.D

10.1038/s41423-021-00661-4 130 YangW.YuT.HuangX.BilottaA

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However, we observed for glutathione that the direct-dimension method for LLCs, which enables real-time detection of chemical kinetics, also preserves significant lifetimes, as detailed below