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A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

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E., Smakhtin

With less ATP, the rest of the cell also becomes sluggish

We treated cells with both iHAP1 [16], a PP2A agonist, and LB-100 [17], an inhibitor of PP2A, and showed that iHAP1 mediated the activation of PP2A mitigated hypoxia-induced neuronal death (Supplemental Fig