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In pathological situations such as hemochromatosis that lead to primary iron overload, iron supplementation may cause ferroptosis in organs outside the gastrointestinal tract as well

10.2147/DMSO.S299375 94 LiuT.ZhangY.WuZ.ZhaoC.DongX.GongH.et al (2024)

Biol Trace Elem Res 186:3151

Redox reactions regulate signal transduction as important chemical processes

The Env spikes on HIV are sparsely distributed, which is consistent with neutralization by monovalent antibody binding in many cases, although it has also been proposed that divalent binding may occur in the context of clustered spikes associated with viral entry 16

Understanding CHAC1 regulation and function across different cancer types can provide insights for potential therapies