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10.1002/glia.23250 [DOI] [PMC free article] [PubMed] [Google Scholar] 84.Lucas SJ, Michel CB, Marra V, Smalley JL, Hennig MH, Graham BP, et al

8 Functionally, the gut microbial metabolic profile of ALD patients undergoes profound changes, highlighted by the depletion of SCFAs (such as butyrate and propionate) and anti-inflammatory microbial metabolites (such as indole-3-propionic acid (IPA)), alongside increased production of microbially derived ethanol and endotoxins

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This results in a high signal-to-noise ratio and a low detection limit which in general means that the detection limit (OD 0.5) is 3 ng per well (100 L)

Interestingly, some of these disorders also occur as acquired syndromes, in the course of myelodysplastic syndromes and acute leukemia

Konopleva M, Cortes J, S-C C, Hayes K, Giles F, OBrien S, Kantarjian H, Andreeff M , Estey E