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Endogenous redox sensors ( e.g

Hemoglobin 32 , 601607 (2008)

Building upon these observations, recent studies have examined how NO-induced disturbances in calcium and redox signalling contribute to ER dysfunction and cellular stress, highlighting a conserved Ca 2+ -NO-redox module observed across kingdoms

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25 mM HEPES-KOH, pH 7.4, 225 mM mannitol, 1 mM EDTA) containing 30% Percoll and centrifuged at 95,000 g for 30 min at 4 C using a swing rotor