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36 159 A recent proteomics and genomics analysis revealed that the protein expression levels of ALDH1B1, ALDH2, and ALDH3B1 are reduced, indicating the loss of liver-specific metabolic functions in patients with HBV-related HCC, and that this reduction may promote tumor progression by increasing the accumulation of exogenous compounds

Liver Support and Protection NAC is widely used in medical settings to treat liver toxicity

Acknowledgements This study was supported financially by the Swiss National Science Foundation (P500PM_203208 to AC) and the University of Oxford Medical Sciences Internal Fund (Pump-Priming, 0014920 to AC)

doi: 10.3390/PHARMACEUTICS15102406 101 KontoghiorghesGJKontoghiorgheCN

The health benefits of collagen reach far beyond its beauty-boosting abilities

This simple sequence of amino acid residues not only has the capability of tissue regeneration and the enhancement of collagen and glycosaminoglycans synthesis but also is able to increase nerve outgrowth and angiogenesis