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Subgroup analysis showed the strongest effects in overweight and obese individuals who also engaged in lifestyle modifications

Vitamin B12 is crucial for regulating sleep-wake cycles because it increases melatonin production in the body

Nat Clin Pract Endocrinol Metab

Individuals typically notice a reduction in fatigue within 48 to 72 hours after a B12 injection

Curtis, MD, MS, MPH, a professor of medicine in the division of clinical immunology and rheumatology at the University of Alabama at Birmingham (UAB), told the American College of Rheumatology in a press release