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3.6.1 Natural compounds: ferroptosis activators with tumor selectivity Natural compounds selectively induce ferroptosis in renal cancer cells while sparing normal kidney tissue, offering a therapeutic window for precision oncology

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Jones et al., 2005

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Therefore, it is valuable to reveal the mechanism involved in the regulation of GPX4 in human cancer cells

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Iron supplementation enhances RSL3-induced ferroptosis to treat naive and prevent castration-resistant prostate cancer

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All four included studies described positive effects on the maintenance and progression of spermatogenic processes (Table 1)

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Sep 2014;33(3):223-227

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