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Plasmids and lentivirus production Plasmids The all-in-one CRISPRi plasmid encoding dCas9-KRAB and sgRNA were obtained from Addgene (catalogue no

The nanoparticles were synthesized using a double emulsion-solvent evaporation method, then functionalized with albumin to enhance BBB permeability

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Additionally, non-pharmacological interventions such as cognitive training, cognitive behavioural therapy, and art or light therapy, previously deemed exotic, are now beginning to be integrated into therapeutic guidelines

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