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Based on studies of these mutants, distinct apical and basolateral iron transport systems possibly exist that function coordinately to transfer iron from intestinal lumen to plasma

(PubMed) Zeisel SH, Blusztajn JK

Oral administration introduces too many variables: fed vs fasted state, gut transit time, individual differences in hepatic enzyme expression, co-administration of CYP3A4 inhibitors or inducers

Supply of methionine and arginine alters phosphorylation of mechanistic target of rapamycin (mTOR), circadian clock proteins, and -s1-casein abundance in bovine mammary epithelial cells