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The term brain insulin resistance has been suggested to describe decreased sensitivity of CNS pathways to insulin, followed by disturbances in synaptic, metabolic and immune response functions (Hoyer 1998)

2.1 The Role of Ferroptosis in Atherosclerosis AS is a chronic progressive vascular disease characterized by disturbances in lipid metabolism (Weber and Noels 2011) and narrowing of the arterial lumen through the formation of atherosclerotic plaques in the arterial wall (Veseli et al., 2017

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However, we could not identify the potential motif for vacuolar targeting that is conserved between AsGGT2 and AtGGT4

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