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( Epub 2021 Dec 23 )

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PMID: 30681787

radicals depend on the local environment with numerous possible reaction pathways, including tryptophan oxidation to kynurenine 39 , L- to D-isomerisation 40 and backbone cleavage 12

This reflects findings made in PD patients, thereby demonstrating a higher immune-related face validity of the AAV1/2-A53T-SYN mouse model compared to the toxin-induced MPTP and 6-OHDA models

10.1016/j.neuron.2018.07.023 Neuron 273 ZhangG