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Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor kappaB to modulate tumour necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants

10.3389/fimmu.2022.1007737 159 WangF.LiuY.LiG.YangX.GaoQ

If your concern is mild pigmentation or an uneven complexion, consistent use of topical brightening ingredients often provides gradual, long-term improvement