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Lipedema is characterized by a symmetrical accumulation of subcutaneous fat, primarily in the lower body, which is often painful and not necessarily associated with elevated overall body mass index (BMI)

F.Mikhail KellawanJ.GurdB.TschakovskyM

3.4.4 EVs have potential value in the diagnosis and treatment of asthenozoospermia EVs can serve as biomarkers for AS diagnosis

In summary, the reactive tendinopathy stage is a short-term adaption to tendon overload, which thickens the tendon, reduces stress and increases stiffness

In colorectal cancer, KRAS-mutant tumors exhibit greater lactate production than wild-type tumors, and elevated lactate levels resulting from KRAS mutations sensitize tumor-specific cytotoxic CD8 + T cells to activation-induced cell death (AICD) by suppressing NF-B activity, thereby reducing their infiltration into the tumor microenvironment (302)