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Topical salicylic acid, podophyllin, urea, and calcipotriol need frequent application, while TCA peel is done in two to three sessions

Glutathione also works in close partnership with other antioxidants recycling vitamin C and vitamin E back into their active forms after they have neutralized free radicals, extending the body's overall antioxidant capacity

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Treatment approaches also remain ambiguous, with no comparative data on the efficacy of chelation therapy alone, versus its use with immunosuppression, or simple discontinuation of the cosmetic agent

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