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Includes missed dose guidance and flexibility notes

244 In addition to solid tumors, NF-B signaling has also been implicated in the microenvironment of hematologic tumors, and it has been demonstrated that NF-B drives pro-survival, genetic instability, and immune evasion in refractory or relapsed diffuse large B-cell lymphoma

polypeptide drugs and compounds of interest from which the drug moiety may be derived include, but are not limited to: Blood and hemopoietic system drugs antianemia drugs, blood coagulation drugs (hemostatics, anticoagulants, antithrombotics, thrombolytics, blood proteins and their fractions), hemoglobin

L.Gomez-CabreraM.-C.VinaJ

PMID: 38279937

Using in vitro cellular models derived from human iPSCs, vitamin C treatment has been shown to increase telomerase activity and the expression of genes encoding telomerase-related RNA and protein components that protect telomere stability (Wei et al., 2012