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[DOI] [PMC free article] [PubMed] [Google Scholar] 199.Choi J et al

Impaired Mitochondrial Respiration in REM-Sleep Behavior Disorder: A Biomarker of Parkinsons Disease

Since mitochondria are essential to our very existence, it is unsurprising that the effects of mitochondrial diseases can be severe, and sometimes lethal, spanning a wide-ranging spectrum of physiological and biochemical symptoms [1,3,4] (see Table 1 for examples)

In addition, glutamate can enhance the production of mtROS through opening of the mitochondrial permeability transition pore (MPTP) and trigger dissipation of the mitochondrial transmembrane potential and depletion of ATP [117, 118]

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Cyclodextrins: Potential therapeutics against atherosclerosis