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Thus, the finding of GluN2B subunit-dominant NMDARs suggests that there is the delay of the developmental trajectory of NMDARs in human iPSC-derived neurons

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Our group recently generated a stable spheroid PDCL from a patient with a high-grade BRAF V600E mutated tumor that also carried a TP53 and RB mutation (STN-10049) ( in vitro , although a marker for therapy resistant cells CD133 ( Several PDCLs representing various BRAF V600E -mutated CNS tumor subtypes have been generated and published by individual labs (see Table 1 for a comprehensive list), and these lines are important novel tools available to investigators

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