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Different levels of peptides, amino acids, free fatty acids, and volatile substances are released in cheeses as a result of these three crucial biological events (149)

Upregulation of peripheral nitric oxide (NO), a vaso-relaxant

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Moreover, the TMPRSS6 gene is related to iron metabolism and plays a role in regulating iron absorption in the intestine and iron storage and release in the liver

Duncan MR, Berman B, Nseyo UO

This suggests a negative feedback loop, where AMPK activation, in response to reduced cellular energy, results in the suppression of the MVA pathway via the phosphorylation of HMGCR and SREBPs