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A never-ending bidirectional cross-talk

Mesothelioma Pemetrexed in combination with cisplatin is indicated for the treatment of patients with malignant pleural mesothelioma whose disease is unresectable or who are otherwise not candidates for curative surgery

Kwon et al

Bone marrow suppression is a significant concern with Alimta, which can lead to neutropenia (low white blood cells), thrombocytopenia (low platelets), and anemia (low red blood cells)