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The process of Se-induced apoptosis is associated with Se chemical species and their metabolism, altering some cellular morphologies including nuclear breakdown, chromatin condensation, membrane blebbing, cell rounding, and formation of apoptotic bodies that are eliminated via phagocytosis [257]

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Turhan A, Weiss LA, Mohandas N, Coller BS, Frenette PS (2002) Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm

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