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However, it exhibits low cell membrane permeability and demonstrates substantial toxicity in animal models, thereby constraining its potential application as a therapeutic agent (Zweygarth et al., 1986)

BST2 also inhibits apoptosis [197]

The mechanism of nicotinic acids antilipemic effect is unknown but is unrelated to its biochemical role as a vitamin

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StatPearls [Internet], 2023 June Takaaki Sugihara, Masahiko Koda, Toshiaki Okamoto, Kenichi Miyoshi, Tomomitsu Matono, Kenji Oyama, Keiko Hosho, Jun-ichi Okano, Hajime Isomoto, Yoshikazu Murawaki

Inhibition of NF-B/EAAT3 leads to increased ROS generation and heightened sensitivity to ferroptosis induced by RSL3