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To the best of our knowledge, our study is the first to identify a pro-BDNF activity for H

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An alternative line of investigation has focused on using immune cells as direct antifibrotic mediators

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Key contributors to atherogenesis include oxidative stress (excess ROS oxidizing lipids and damaging endothelial cells), vascular inflammation (cytokine and chemokine release recruiting more immune cells), endothelial dysfunction (reduced NO bioavailability and loss of barrier integrity), and dyslipidemia (elevated LDL/triglycerides and low HDL)

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When there is an imbalance between oxidants and antioxidants in the liver, oxidative stress occurs, thereby impairing liver function

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