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10.1016/j.jssc.2022.123383 [Google Scholar] Werlang EB, Julich J, Muller MVG, de Farias Neves F, Sierra-Ibarra E, Martinez A, de Schneider R (2020) Bioethanol from hydrolyzed Spirulina ( Arthrospira platensis ) biomass using ethanologenic bacteria

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The accumulation of -amyloid increases oxidative stress and intracellular Ca 2+ influx, promoting neuronal toxicity in cases of Alzheimers disease ( in vitro studies on other natural compounds and computational or theoretical approaches, and should therefore be considered hypothetical, as direct in vitro or in vivo experimental data specific to bromelain are lacking

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Consequently, the results indicated that SMR may inhibit the TNF signaling pathway by modulating the expression of COX-2, IL-6, and TNF- (143)