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DOI: 10.1038/s41467-020-20790-0 Frontiers in Physiology (2025) MOTS-c treatment restored mitochondrial respiration in type 2 diabetic hearts, improved fasted blood glucose, and improved glucose handling in T2D rat models, consistent with AMPK pathway activation and increased mitochondrial biogenesis markers

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Without these nutrients, your body may not metabolize fat as well as it could, leading to metabolic dysfunction and weight gain

Stress management Chronic stress elevates cortisol, which suppresses tissue repair and promotes catabolism

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[11] [12] Symptoms include fatigue, weakness, shortness of breath, and palloreffects that could significantly impact quality of life and may be mistakenly attributed to other causes in patients managing multiple health conditions