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In this study, the levels of total iron, Fe 2+ , and Fe 3+ in the blood increased, suggesting that intestinal mucosal cells were damaged by intestinal I/R injury and ferroptosis occurred, and the iron in the cells was released into the blood, which increased the blood iron concentration

The combined effects of these factors caused lipid peroxidation and mitochondrial injury, and then triggered the burst of ROS, resulting in cell injury, which eventually produced initial conditions for the formation of urolithiasis

Wrote the paper: RP WLB

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Increased micronuclei and nuclear abnormalities in buccal mucosa and oxidative damage in saliva from patients with chronic and aggressive periodontal diseases